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Index | Go Back | Email This Information | Print Untitled Document Chemotherapy

Definition

Chemotherapy is a treatment of cancer. It uses chemicals that kill cancer cells.

Parts of the Body Involved

Chemotherapy can be given in a number of ways. The body areas that are involved will depend on the method chosen.

Reasons for Procedure

This is used to treat cancer. The goal is to reduce the number of cancer cells or decrease the size of tumors.

Risk Factors for Complications During the Procedure

  • History of allergies
  • Debilitation

What to Expect

Prior to Procedure

You may be asked to take some pre-medications such as:

  • Steroids
  • Allergy medications (anti-histamines)
  • Anti-nausea medications
  • Sedatives
  • Antibiotics

Anesthesia

Anesthesia is not used.

Description of the Procedure

Your doctor will talk to you about the best route for the chemotherapy medication(s). You may also be given other medications to fight the side effects.

Chemotherapy drugs may be given in several ways:

  • By mouth
  • By injection into a muscle or vein (intravenously)
  • By catheter into the bladder, abdomen, chest cavity, brain, spinal cord, or liver
  • By application to the skin

Chemotherapy Through Cardiovascular System

Chemotherapy

© 2009 Nucleus Medical Art, Inc.

After Procedure

You may be given any of the following:

  • Medications to take at home to make you more comfortable (eg, anti-nausea drugs)
  • Injections of an immune-system boosting drug several days after your chemotherapy has been administered (this will increase your white blood cells and fight potential infections)
  • Other drugs, including steroids, allergy medications (anti-histamines), anti-nausea medications, sedatives, and antibiotics

How Long Will It Take?

This depends on the route used, the number of medications, and the amount of each medication. A session may be as brief as the time it takes to swallow a pill. I could also take several hours or last overnight. In one type medication is slowly delivered over a week.

Will It Hurt?

The treatment may cause a number of uncomfortable side effects. The delivery of the chemotherapy does not usually hurt. It may hurt if the needle is misplaced. Medication can then leak into your tissue and cause damage. If this happens, tell your doctor or nurse.

Possible Complications

  • Nausea and/or vomiting
  • Diarrhea or constipation
  • Appetite loss
  • Hair loss
  • Anemia
  • Weakened immune system and increased susceptibility to infection
  • Intense fatigue
  • Decreased platelet count and easy bruising and/or bleeding
  • Mouth sores
  • Numbness, tingling, or weakness due to nerve damage
  • Kidney damage
  • Damage to the heart muscle
  • Infertility
  • Cessation of the menstrual period

Average Hospital Stay

Chemotherapy is most often done as an outpatient procedure. If you experience excessive vomiting, you may need to be admitted to the hospital. They will give you IV fluids with your treatments.

Postoperative Care

  • Get a lot of sleep.
  • Try to eat as healthfully as possible. Appetite changes can be a challenge.
  • Drink lots of fluids to avoid dehydration. It will flush the medications out of your kidneys as quickly as possible.
  • Use special mouth rinses to avoid or treat mouth sores.
  • Administer post-chemotherapy shots if they are prescribed by your doctor. These will help to keep your white blood count stable.
  • Try to avoid people with communicable diseases (particularly children). The process will compromise your immune system. Viral illness (eg, cold or flu) can have serious effects.

Outcome

Chemotherapy should help decrease the number of cancer cells and shrink tumors.

Your doctor may order any of the following tests to check the progress of your treatment:

  • Blood tests
  • Urine tests
  • X-rays
  • Ultrasound —a test that uses sound waves to find tumors
  • MRI scan —a test that uses magnetic waves to make pictures of the inside of the body
  • CT scan —a type of x-ray that uses a computer to make pictures of the inside of the body
  • Bone scans —a type of x-ray that shows areas of unusual activity
  • Bone marrow biopsies —the removal of a sample of bone marrow for examination

Call Your Doctor If Any of the Following Occurs

  • Sores in your mouth or lip blisters
  • White patches in your mouth
  • Difficulty/pain with swallowing
  • Diarrhea or constipation
  • Vomiting that prevents you from holding down fluids
  • Blood in your vomit
  • Easy bruising
  • Nosebleeds, bleeding gums, new vaginal bleeding
  • Blood in your urine or stool
  • Burning or frequency of urination
  • Chest pain
  • Severe weakness
  • Shortness of breath, cough
  • Calf pain, swelling, or redness in the legs or feet (which could signify a blood clot)
  • Abnormal vaginal discharge, itching, or odor
  • Signs of infection, including fever and chills
  • Pain in a new location
  • Numbness, tingling, or pain in your extremities
  • Redness, swelling, increasing pain, excessive bleeding, or a "pimple" at the site of your IV
  • Headache, stiff neck
  • Hearing or vision changes
  • Exposure to someone with an infectious illness, including chickenpox
  • Fever (a fever after chemotherapy in the presence of a low white blood cell count, called a neutropenic fever; the doctor will likely admit you to the hospital)

RESOURCES:

American Cancer Society
http://www.cancer.org/

National Cancer Institute
http://www.cancer.gov/

Nemours Foundation
http://www.nemours.org/

CANADIAN RESOURCES:

Cancer Care Ontario
http://www.cancercare.on.ca/

Canadian Cancer Society
http://www.cancer.ca/

References:

Clinical Oncology . 2nd ed. Churchill Livingstone; 2000.

National Cancer Institute website. Available at: http://www.cancer.gov/ .

National Institutes of Health website. Available at: http://www.nih.gov/ .



Last reviewed December 2008 by Igor Puzanov, MD

Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.

All EBSCO Publishing proprietary, consumer health and medical information found on this site is accredited by URAC. URAC's Health Web Site Accreditation Program requires compliance with 53 rigorous standards of quality and accountability, verified by independent audits.

Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.

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